Pooled Analysis of Change in Global Cognitive Function (Measured by MMSE), AChEIs and Memantine Compared with Placebo, by Medication TypeĮFigure 9. Pooled Analysis of Change in Global Cognitive Function (Measured by ADAS-Cog-11), AChEIs and Memantine Compared with Placebo, by Medication TypeĮFigure 8. Test Accuracy of Longer, Self-Administered Tests (KQ 2)ĮFigure 7. Test Accuracy of Brief Screening Tests Reported in 1 Study (KQ 2)ĮFigure 6. Test Accuracy of Very Brief Screening Tests Reported in 1 Study (KQ 2)ĮFigure 5. Test Accuracy of Brief Screening Tests Reported in More Than 1 Study (KQ 2)ĮFigure 4. Bivariate Pooled Analysis of Test Accuracy of the MMSE to Detect Dementia at a Cut-off of ≥23 or ≥24 (KQ)ĮFigure 3. Test Accuracy of Very Brief Screening Tests Reported in More Than 1 Study (KQ 2)ĮFigure 2. Caregiver and Caregiver-Patient Dyad Interventions: Summary of Results, by Intervention (KQ 4 and 5)ĮFigure 1. Patient-Level Nonpharmacologic Interventions: Summary of Results, by Intervention (KQ 4 and 5)ĮTable 8. Other Medications and Supplements: Summary of Results, by Agent (KQ 4 and 5)ĮTable 7. AChEIs and Memantine: Summary of Results, by Medication Type (KQ 4 and 5)ĮTable 6. Trial and Population Characteristics: Summary Across All Intervention Types (KQ 4 and 5)ĮTable 5. Study and Population Characteristics of Included Diagnostic Accuracy Studies (KQ 2)ĮTable 4. Study Design-Specific Quality Rating Criteria*ĮTable 3. Literature Search Strategies for Primary LiteratureĮTable 2. Publication type: Ancillary study to excluded primary study.ĮMethods. Quality: Study did not meet criteria for fair or good quality. Study design: Not an included study design comparative effectiveness follow-up less than 3 months (does not apply to harms) case-control design (KQ2 only) cohort or case-control (with n<1000) (KQ5 only). Intervention: Study used an excluded intervention or screening approach or intervention aim irrelevant. Population: Study population not relevant (age <65 years exclusively populations with mental health illnesses or chronic disease severe dementia professional caregivers otherwise not representative community-dwelling population). Outcomes: Study did not report relevant outcomes. Setting: Study was not conducted in a country relevant to US practice or study was conducted in intermediate care facility or otherwise unrepresentative setting. AArticles could be assessed for more than 1 KQ.īReasons for exclusion: Aim: Study aim not relevant.
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